From charming child star to Hollywood powerhouse, Hayden Panettiere left her mark on both television and film. Whether she was stealing the spotlight as a country superstar in “Nashville,” defying gravity as a cheerleader in “Bring It On: All or Nothing,” or opening up in her bestselling autobiography “This Is Me: A Reckoning,” she proved tenfold that she could do it all. As one of the 2000s hottest it-girls, Panettiere’s legacy will surely be remembered for years to come.

Ahead, take a look back on her multi-decade career as one of Hollywood’s most unforgettable leading ladies.