Venezuelan President Nicolas Maduro at the Miraflores Presidential Palace in Caracas, on October 15, 2021. - Federico Parra/AFP/Getty Images

Prosecutors in New York are expected to bring new charges against former Venezuelan President Nicolás Maduro and his wife Cilia Flores over the alleged torture of Americans who were held in Venezuelan government custody in recent years, according to multiple people familiar with the investigation.

An announcement could come as soon as Thursday, the people said.

The new charges relate to what the US government has said was the wrongful detention of more than a dozen US citizens in Venezuelan prisons during t...