A man riding a “two-wheeled device” was fatally struck by a pick-up truck driver in the Bronx during the Wednesday morning rush, police said. 

The unidentified man was heading west on East 145th Street when the truck driver, traveling south on Brook Avenue in Mott Haven, hit him around 8:25 a.m., cops said. 

He was taken with head and body trauma to Lincoln Medical Center, where he was pronounced dead. 

The unidentified rider was fatally struck around 8:25 a.m. at East 145th Street and Brook Avenue in Mott Haven, cops said. Google Maps

The pick-up truck driver, a 55-year-old man, stayed at the scene and did not immediately face any charges, police said. 

It was not immediately clear whether the man who was killed had been riding a bike, scooter or moped.

His name was not released pending family notification.

The fatal crash happened just two days after a 71-year-old bicyclist was killed when he crashed into a dog running free in Central Park, police said. 

The victim was taken with head and body trauma to Lincoln Medical Center, where he succumbed to his injuries. Getty Images

Douglas Adams was riding north on the East Drive near East 84th Street around 8:20 a.m. Monday when he struck the unleashed Golden Retriever that darted into the roadway, police and the sources said.

The impact catapulted the senior over the handlebars and headfirst into the pavement, police said. 

He was rushed to Weill Cornell Medical Center, but could not be saved. 

And last week, a delivery woman was killed when a dump truck plowed into her e-bike and then drove off in the heart of Herald Square, according to cops and an advocacy group.

The truck driver collided with the 50-year-old cyclist the morning of Sept. 28, as both headed west on West 34th Street, approaching Seventh Avenue, police said. 

The woman — who was riding a JOCO rental e-bike and making a delivery — was pronounced dead at the scene.