Donald Trump is making a shocking claim about his political enemies ... alleging people committed suicide over the way they were treated by Joe Biden's administration.

POTUS dropped the claim during his full WABC interview with former fixer-turned-foe-turned-friend Michael Cohen Sunday ... but didn't identify who he was talking about or offer evidence to support it.

Trump said, "We had many suicides, people committed suicide over this" ... before blaming what he called vicious people in the Biden administration -- and taking a swipe at Barack Obama's administration, too.

He then turned his fire on former government officials who've since landed jobs in the private sector and media ... claiming some now work at Microsoft and others appear on CNN.

Trump specifically went after former FBI personnel who became TV commentators ... calling them "FBI slobs" and accusing them of being "dirty cops."

There wasn't much context given for exactly which investigations or individuals Trump was talking about ... and he didn't name anyone he says died by suicide.

The remarks came during Trump's newly repaired relationship with Cohen -- once his longtime personal lawyer before the two became bitter enemies.

As TMZ previously reported ... Cohen told us last month the two were "reconciling" and putting their past aside after private meetings at Bedminster and Mar-a-Lago.

Now they're back talking publicly ... and Trump definitely didn't hold back.

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