A London rape trial against British comedian and actor Russell Brand is slated to kick off Wednesday with jurors expected to hear opening statements in the case alleging the actor sexually assaulted six women.

The 51-year-old “Get Him to the Greek” star’s case is expected to unfold in Southwark Crown Court in Central London before a jury of eight men and four women who were selected on Monday and Tuesday, the Guardian reported.

Brand is charged with three counts of rape, three counts of sexual assault, and one count of indecent assault tied to alleged incidents that occurred between 1999 and 2009.

“The Forgetting Sarah Marshall” actor allegedly raped a women in a Bournemouth hotel room at a Labour Party conference; groped a television worker’s breasts and forced her to engage in a sex act with him in a bathroom; and kissed a grabbed a radio station worker, prosecutors alleged at previous hearings.

Brand in May 2025, was initially hit with two counts of rape, two counts of sexual assault and one count of indecent assault for alleged incidents from 1999 and 2005.

Then prosecutors slapped additional charges against him connected to alleged assaults of two other women in London in 2009.

Brand, who has been out on bail, pleaded not guilty and maintains that all of his sexual encounters were consensual. The trial could last 6-10 weeks.

Brand’s wife, Laura Gallacher, accompanied him to court Monday. The pair have been married for nine years and have three kids who they are raising in Florida as Brand pivoted his career toward podcasting.

Brand was famously married to pop singer Katy Perry from 2010 until their divorce in 2012.

He rose to fame in the 2000s as a TV personality, hosting shows like the 2007 Brit Awards and the MTV Video Music Awards — and also had his own BBC radio show.

Then Brand made the leap to Hollywood starring in movies including “Rock of Ages.”

Brand — who previously battled with substance abuse — now podcasts about topics including self-help, spirituality and political conspiracy theories.

The identities of victims of sexual abuse are barred from public disclosure for life under British laws.

With Post wires